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1. What is the synaptic basis of plasticity in neocortex?
2. Cite and summarize the primary literature on the role of the hippocampus in the storage and retrieval of sequence memories (learning of a temporal sequence of stimuli).
3. A fictional neurophysiological preparation allows monitoring of the action potentials in 10000 optic nerve axons making up the outputs of a roughly circular collection of contiguous ganglion cells of a retina (upon which experimenter-controlled optical stimuli can be presented). Propose a method for measuring the information content of each of these 10000 axons as a function of time.
4. Experimentally, scientists report virtually a zoo of neuronal subtypes. But suppose all we had were cells with true Hodgkin-Huxley squid axon dynamics. Is that enough for sensory coding? Computation? Muscular control?
